Comparison

Doramapimod European Partner

Item no. TMO-T6277-25mg
Manufacturer TargetMol
CASRN 285983-48-4
Amount 25 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Citations 1. Pargellis C, et al. Nat Struct Biol, 2002, 9(4), 268-272.
Smiles Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias BIRB 796
Shipping Condition Cool pack
Available
Manufacturer - Targets
Raf|||Autophagy|||p38 MAPK
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
527.66
Description
Doramapimod (BIRB 796) is a highly potent inhibitor of p38 MAPK (Kd: 0.1 nM), but weakly inhibits c-RAF, Fyn, Lck, ERK-1, SYK, IKK2, and ZAP-70.
Pathways
Autophagy|||MAPK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 25 mg
Available: In stock
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