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PHA-680632

PHA-680632

Item no.	TMO-T6338-50mg
Manufacturer	TargetMol
CASRN	398493-79-3
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Smiles	CCc1cccc(CC)c1NC(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PHA 680632,PHA680632
Similar products	398493-79-3
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PLK\|\|\|FGFR\|\|\|Aurora Kinase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	501.62
Description	PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
Pathways	Tyrosine Kinase/Adaptors\|\|\|Angiogenesis\|\|\|Cell Cycle/Checkpoint\|\|\|Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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