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Caffeic Acid Phenethyl Ester

Caffeic Acid Phenethyl Ester

Item no.	TMO-T6429-1ml
Manufacturer	TargetMol
CASRN	104594-70-9
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Phenylethyl Caffeate,CAPE
Similar products	104594-70-9
Shipping Condition	Cool pack
Available
Manufacturer - Targets	NF-κB\|\|\|Apoptosis
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	284.31
Description	Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective and immunomodulating activities. CAPE is the phenethyl alcohol ester of caffeic acid and a bioactive component of honeybee hive propolis. In addition, CAPE inhibits PDGF-induced proliferation of vascular smooth muscle cells through the activation of p38 mitogen-activated protein kinase (MAPK) and hypoxia-inducible factor (HIF)-1alpha and subsequent induction of heme oxygenase-1 (HO-1).
Pathways	Apoptosis\|\|\|NF-κB

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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