Comparison

Dovitinib lactate hydrate European Partner

Item no. TMO-T6479-200mg
Manufacturer TargetMol
CASRN 915769-50-5
Amount 200 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Smiles O.CC(O)C(O)=O.CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias Dovitinib (TKI258) Lactate,Dovitinib Lactate,TKI258
Shipping Condition Cool pack
Available
Manufacturer - Targets
c-Kit|||PDGFR|||FGFR|||VEGFR|||FLT
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
482.51
Description
Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors
Receptor
c-Kit; FGFR1; FGFR3; FLT3; VEGFR3/FLT4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 mg
Available: In stock
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