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Indoximod

Indoximod

Item no.	TMO-T6543-200mg
Manufacturer	TargetMol
CASRN	110117-83-4
Amount	200 mg
Quantity options	1 mL x 10 mM (in DMSO) 10 mg 1 g 200 mg 250 mg 500 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,995
Citations	1. Hou DY, et al. Cancer Res. 2007, 67(2), 792-801.
Smiles	Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	NLG-8189,Indoximod (NLG-8189),1-Methyl-D-tryptophan
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Indoleamine 2, 3-Dioxygenase (IDO)
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	218.25
Description	Indoximod (NLG-8189) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
Pathways	Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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