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Nutlin-3b

Nutlin-3b

Item no.	TMO-T6614-2mg
Manufacturer	TargetMol
CASRN	675576-97-3
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,9883
Citations	1. Vassilev LT, et al. Science, 2004, 303(5659), 844-848.
Smiles	COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCNC(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	(+)-Nutlin-3
Shipping Condition	Cool pack
Available
Manufacturer - Targets	E1/E2/E3 Enzyme\|\|\|Mdm2
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	581.49
Description	Nutlin-3b ((+)-Nutlin-3) is a p53/MDM2 antagonist or inhibitor (IC50: 13.6 μM), 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.
Pathways	Apoptosis\|\|\|Ubiquitination

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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