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Sabutoclax

Sabutoclax

Item no.	TMO-T6650-2mg
Manufacturer	TargetMol
CASRN	1228108-65-3
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Citations	1. Wei J, et al. J Med Chem, 2010, 53(10), 4166-4176
Smiles	CC(CNC(=O)c1c(O)c(O)cc2c(O)c(c(C)cc12)-c1c(C)cc2c(C(=O)NC[C@H](C)c3ccccc3)c(O)c(O)cc2c1O)c1ccccc1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	BI-97C1
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Bcl-2 Family
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	700.78
Description	Sabutoclax (BI-97C1)(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
Pathways	Apoptosis
Bioactivity	Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 uM, 0.32 uM, 0.20 uM and 0.62 uM, respectively.
Receptor	Mcl-1 , Bcl-xL , Bcl-2 , Bfl-1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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