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WYE-354

WYE-354

Item no.	TMO-T6731-1ml
Manufacturer	TargetMol
CASRN	1062169-56-5
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 20 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	COC(=O)Nc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCN(CC3)C(=O)OC)c2n1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Similar products	1062169-56-5
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PI3K\|\|\|Autophagy\|\|\|Apoptosis\|\|\|mTOR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	495.53
Description	WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kα (>100-fold) and PI3Kγ (>500-fold).
Pathways	PI3K/Akt/mTOR signaling\|\|\|Apoptosis\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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