Comparison

APS-2-79 hydrochloride European Partner

Item no. TMO-T6760-50mg
Manufacturer TargetMol
CASRN 2002381-31-7
Amount 50 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Citations 1.Dhawan NS, et al. Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling. Nature. 2016 Sep 1;537(7618):112-116.
Smiles Cl.COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3C)c2cc1OC
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias APS-2-79 HCl
Shipping Condition Cool pack
Available
Manufacturer - Targets
MEK|||MAPK
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
423.89
Description
APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.
Pathways
MAPK

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 mg
Available: In stock
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