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AS1842856

AS1842856

Item no.	TMO-T6762-200mg
Manufacturer	TargetMol
CASRN	836620-48-5
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Neuroscience Targets for Rodent Neurosciences Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1.Nagashima T, et al. Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice. Mol Pharmacol. 2010 Nov;78(5):961-70.
Smiles	CCn1cc(C(O)=O)c(=O)c2c(N)c(F)c(NC3CCCCC3)cc12
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Autophagy\|\|\|FOXO1
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	347.38
Description	AS1842856 is a Foxo1 inhibitor (IC50=30 nM) that specifically blocks the transcriptional activity of Foxo1 and reduces its activity by directly binding to activated FoxO1. AS1842856 has autophagy inhibitory activity.
Pathways	Apoptosis\|\|\|Autophagy

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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