EAI045

Item no.	TMO-T6824-25mg
Manufacturer	TargetMol
CASRN	1942114-09-1
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Signaling Reagents & Chemicals Molecules By Organ Bladder Cancer
Type	Molecules
Specific against	other
Citations	1.Jia Y et al. Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors. Nature. 2016 May 25;534(7605):129-32.
Smiles	Oc1ccc(F)cc1C(N1Cc2ccccc2C1=O)C(=O)Nc1nccs1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	EGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	383.4
Description	EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.
Pathways	Tyrosine Kinase/Adaptors\|\|\|JAK/STAT signaling\|\|\|Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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