FLLL32

Item no.	TMO-T6838-50mg
Manufacturer	TargetMol
CASRN	1226895-15-3
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Reagents & Chemicals Molecules By Organ Bone Cancer
Type	Molecules
Specific against	other
Citations	1. Fossey SL., et al. The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. BMC Cancer. 2011 Mar 28;11:112.
Smiles	COc1ccc(\C=C\C(=O)C2(CCCCC2)C(=O)\C=C\c2ccc(OC)c(OC)c2)cc1OC
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	JAK inhibitor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	JAK\|\|\|STAT\|\|\|Apoptosis
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	464.55
Description	FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).
Pathways	Apoptosis\|\|\|Chromatin/Epigenetic\|\|\|Angiogenesis\|\|\|Stem Cells\|\|\|JAK/STAT signaling\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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