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Monomethyl auristatin E

Monomethyl auristatin E

Item no.	TMO-T6897-500mg
Manufacturer	TargetMol
CASRN	474645-27-7
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Metabolism Diabetes Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Citations	1. Francisco JA, et al. Blood. 2003, 102(4), 1458-1465.
Smiles	CC[C@H](C)C([C@@H](CC(=O)N1CCC[C@H]1C(OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)[C@@H](C(C)C)C(=O)NC(=O)[C@@H](NC)C(C)C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	MMAE,Vedotin
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|Microtubule Associated\|\|\|ADC Cytotoxin
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	717.98
Description	Monomethyl auristatin E (MMAE) (MMAE), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin and also has inhibition of antibody-drug conjugates (ADCs) activity.
Pathways	Apoptosis\|\|\|Cytoskeletal Signaling\|\|\|Antibody-drug Conjugate/ADC Related
Bioactivity	Monomethyl auristatin E (MMAE) is a synthetic antineoplastic agent, which is linked to a monoclonal antibody (MAB).
Receptor	microtubule

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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