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Necrosulfonamid

Necrosulfonamid

Manufacturer	TargetMol
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Amount	25mg
Item no.	TMO-T6904-25mg
CASRN	1360614-48-7
eClass 6.1	32169090
eClass 9.0	32169090
Available
Short Description	(E)-Necrosulfonamide is an inhibitor of necroptosis. Blocks mixed lineage kinase domain-like protein (MLKL), a critical substrate of receptor-interacting serine-threonine kinase 3 (RIP3) during necrosis. Prevents MLKL-RIP1-RIP3 necrosome complex from interacting with downstream necrosis effectors. Binds and inhibits gasdermin D. Inhibits pyroptosis.
Shipping	cool pack
Storage	-20°
Target names or alias	(E)-Necrosulfonamide
Molecular Weight	461, 47
Pathway	MAPK
Target	MLK

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Amount: 25mg

available

Delivery expected until 6/6/2024