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Pexmetinib

Pexmetinib

Item no.	TMO-T6934-25mg
Manufacturer	TargetMol
CASRN	945614-12-0
Amount	25 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	Cc1ccc(cc1)-n1nc(cc1NC(=O)NCc1cc(F)ccc1Oc1ccc2n(CCO)ncc2c1)C(C)(C)C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	ARRY-614
Shipping Condition	Cool pack
Available
Manufacturer - Targets	p38 MAPK\|\|\|Tie-2\|\|\|Autophagy
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	556.63
Description	Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor studied in acute myeloid leukemia and inhibits osteoclastogenesis and breast cancer-induced osteolysis via the P38/STAT3 signaling pathway.
Pathways	Autophagy\|\|\|Tyrosine Kinase/Adaptors\|\|\|MAPK

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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