RG7112

Item no.	TMO-T6965-10mM
Manufacturer	TargetMol
CASRN	939981-39-2
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Oncology Reagents & Chemicals Molecules By Organ Lung Cancer
Type	Molecules
Specific against	other
Citations	1. Veronica Tisato, et al. MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer. Journal of Hematology & Oncology2017
Smiles	CCOc1cc(ccc1C1=NC(C)(c2ccc(Cl)cc2)C(C)(N1C(=O)N1CCN(CCCS(C)(=O)=O)CC1)c1ccc(Cl)cc1)C(C)(C)C
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	RG-7112,RG 7112,RO5045337
Shipping Condition	Cool pack
Available
Manufacturer - Targets	E1/E2/E3 Enzyme\|\|\|Mdm2
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	727.78
Description	RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.
Pathways	Apoptosis\|\|\|Ubiquitination
Bioactivity	RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor. Phase 1.
Receptor	Mdm2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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