WZB117

Item no.	TMO-T7018-10mM
Manufacturer	TargetMol
CASRN	1223397-11-2
Amount	1 mL x 10 mM (in DMSO)
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Oncology Metabolism Diabetes Reagents & Chemicals Molecules By Organ Breast Cancer
Type	Molecules
Specific against	other
Citations	1.Liu Y,et al. A small-molecule inhibitor of glucose transporter 1 downregulates glycolysis, induces cell-cycle arrest, and inhibits cancer cell growth in vitro and in vivo.Mol Cancer Ther. 2012 Aug;11(8):1672-82.
Smiles	Oc1cccc(c1)C(=O)Oc1cccc(F)c1OC(=O)c1cccc(O)c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	transporter inhibitor
Shipping Condition	Cool pack
Available
Manufacturer - Targets	transporter
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	368.31
Description	WZB117 is a Glucose Transporter 1 (GLUT1) inhibitor. when IC50 of WZB117 approximate 10 μM, it inhibits lung cancer A549 cells and breast cancer MCF7 cells proliferation.
Pathways	Metabolism
Bioactivity	WZB117 is an inhibitor of Glucose Transporter 1 (GLUT1). It inhibited cell proliferation in lung cancer A549 cells and breast cancer MCF7 cells with an IC50 of approximately 10 uM.
Receptor	GLUT1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 1 mL x 10 mM (in DMSO)

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