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Eupatorin

Eupatorin

Item no.	TMO-T7032-10mM
Manufacturer	TargetMol
CASRN	855-96-9
Amount	1 mL x 10 mM (in DMSO)
Quantity options	1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 20 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Purity	0,98
Citations	1. Dole?kova I, et al. Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus, leaves[J]. Fitoterapia, 2012, 83(6):1000-1007.
Smiles	COc1ccc(cc1O)-c1cc(=O)c2c(O)c(OC)c(OC)cc2o1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	P450 inhibitor,
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Cytochromes P450
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	344.32
Description	Eupatorin has antiproliferative and antiangiogenic effects. Eupatorin has antiproliferative and cytostatic effects on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. Eupatorin-induced cell death is mediated by both the extrinsic and the intrinsic apoptotic pathways and through a mechanism dependent on reactive oxygen species generation. Eupatorin also has meaningful anti-inflammatory property.
Pathways	Metabolism
Bioactivity	Eupatorin has antiproliferative and antiangiogenic effects. Eupatorin has antiproliferative and cytostatic effects on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism. Eupatorin-induced cell death is mediated by both the extrinsic and the intrinsic apoptotic pathways and through a mechanism dependent on reactive oxygen species generation. Eupatorin also has meaningful anti-inflammatory property.
Receptor	CYP1; others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mL x 10 mM (in DMSO)

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