Comparison

Upadacitinib European Partner

Item no. TMO-T7503-1mg
Manufacturer TargetMol
CASRN 1310726-60-3
Amount 1 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 20 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Purity 0,9978
Citations 1.Nakayamada S, et al. Recent Progress in JAK Inhibitors for the Treatment of Rheumatoid Arthritis. BioDrugs. 2016 Oct;30(5):407-419.
Smiles CC[C@@H]1CN(C[C@@H]1c1cnc2cnc3[nH]ccc3n12)C(=O)NCC(F)(F)F
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias ABT-494
Shipping Condition Cool pack
Available
Manufacturer - Targets
JAK
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
380.37
Description
Upadacitinib (ABT-494) (ABT-494) is a selective Janus kinase (JAK) 1 inhibitor, which is being studied for the treatment of several autoimmune disorders in the IC50 of 43 nM.
Pathways
Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Stem Cells|||Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mg
Available: In stock
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