Human Tau-441 GSK-3beta-phosphorylated protein, His Tag

Protein

Dry ice

47.9 kDa

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]

Tau

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 47.9 kDa. The protein migrates as 45-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

50 mM Tris, 150 mM NaCl, pH7.5

glycerol