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Mcl-1 inhibitor 3

Mcl-1 inhibitor 3

Item no.	TMO-T11972-25mg
Manufacturer	TargetMol
CASRN	2376774-73-9
Amount	25 mg
Quantity options	100 mg 25 mg 500 mg 5 mg
Category	Oncology By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	[H][C@@]12CC[C@@]1([H])[C@@H](OCCN1CC(F)(F)C1)\C=C/CCN(C)C(=O)C[C@](O)(C(=O)NS(=O)(=O)N(C)C)c1ccc3OC[C@]4(CCCc5cc(Cl)ccc45)CN(C2)c3c1 \|c:18\|
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Bcl-2 Family
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	820.39
Description	Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate macrocyclic Mcl-1 inhibitor (Ki= 0.061 nM; IC50=19 nM in an OPM-2 cell viability assay).
Pathways	Apoptosis

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25 mg

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