PS315

Item no.	TMO-T16671-25mg
Manufacturer	TargetMol
CASRN	1221964-50-6
Amount	25 mg
Quantity options	100 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	C(\CCC1=CC=C(Cl)C=C1)(=C/C(O)=O)/C2=CC=C(C=C2)C3=CC=CC=C3
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PKC
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	362.85
Description	PS315 inhibits the full-length and catalytic domain constructs of PKCζ (IC50=10 μM) and PKCη (IC50=30 μM). PS315 has anti-cancer activity. PS315 is a derivative of PS48 and is an allosteric PKC inhibitor by binding to the PIF-pocket of aPKC and inducing displacement of the active site residue Lys111.
Pathways	Chromatin/Epigenetic\|\|\|Cytoskeletal Signaling

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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