Comparison

Berzosertib European Partner

Item no. TMO-T2669-500mg
Manufacturer TargetMol
CASRN 1232416-25-9
Amount 500 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Molecules
Specific against other
Smiles CNCc1ccc(cc1)-c1cc(on1)-c1nc(cnc1N)-c1ccc(cc1)S(=O)(=O)C(C)C
ECLASS 10.1 32169090
ECLASS 11.0 32169090
UNSPSC 12000000
Alias VX-970,VE-822
Shipping Condition Cool pack
Available
Manufacturer - Targets
ATM/ATR
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
463.55
Description
Berzosertib (VE-822) is an ATR inhibitor (Ki<0.2 nM) that also inhibits ATM (Ki=34 nM). Berzosertib has antitumor activity and has been used in trials investigating the treatment of ovarian tumors, plasmacytoid tumors of the ovary, solid tumors in adults, advanced solid tumors, and advanced solid tumors.
Pathways
PI3K/Akt/mTOR signaling|||DNA Damage/DNA Repair

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
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