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Repotrectinib

Repotrectinib

Item no.	TMO-T4071-100mg
Manufacturer	TargetMol
CASRN	1802220-02-5
Amount	100 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Reagents & Chemicals Molecules By Organ Colorectal Cancer
Type	Molecules
Specific against	other
Smiles	C[C@H]1CNC(=O)c2cnn3ccc(N[C@H](C)c4cc(F)ccc4O1)nc23
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	TPX 0005,TPX0005,TPX-0005
Shipping Condition	Cool pack
Available
Manufacturer - Targets	ALK\|\|\|Src\|\|\|ROS\|\|\|ROS Kinase\|\|\|Trk receptor
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	355.37
Description	Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 values of 1.01 nM for WT ALK, 5.3 nM for SRC, 1.08 nM for ALK L1196M, and 1.26 nM for ALK G1202R.
Pathways	Immunology/Inflammation\|\|\|Angiogenesis\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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