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YHO-13177

YHO-13177

Item no.	TMO-T4595-200mg
Manufacturer	TargetMol
CASRN	912287-56-0
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	COc1ccc(cc1OC)C(=C\c1ccc(s1)N1CCC(O)CC1)\C#N
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	YHO 13177,YHO13177
Shipping Condition	Cool pack
Available
Manufacturer - Targets	BCRP
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	370.47
Description	YHO-13177 is a potent and specific inhibitor of BCRP, which enhances the cytotoxicity of SN-38 in cancer cells without affecting P-glycoprotein–mediated paclitaxel resistance in [MDR1]-transduced human leukemia [K562] cells.
Pathways	Membrane transporter/Ion channel

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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