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N-Acetyl-L-glutamic acid

N-Acetyl-L-glutamic acid

Item no.	TMO-T5267-5g
Manufacturer	TargetMol
CASRN	1188-37-0
Amount	5 g
Quantity options	10 g 1 mL x 10 mM (in DMSO) 25 mg 500 mg 5 g 5 mg
Category	Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	CC(=O)NC(CCC(O)=O)C(O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	Ac-L-Glu-OH,N-Acetylglutamic acid
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Endogenous Metabolite
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	189.17
Description	N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) (NAcGlu) is an acetylated amino acid. NAcGlu is biosynthesized from glutamic acid and acetyl-CoA by the enzyme N-acetyl glutamate synthase (NAGS). NAcGlu activates carbamoyl phosphate synthetase in the urea cycle. A deficiency in N-acetyl glutamate synthase or a genetic mutation in the gene coding for the enzyme will lead to urea cycle failure in which ammonia is not converted to urea, but rather accumulated in the blood leading to the condition called Type I hyperammonemia.
Pathways	Metabolism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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