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PF-562271 besylate

PF-562271 besylate

Item no.	TMO-T6177-200mg
Manufacturer	TargetMol
CASRN	939791-38-5
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Neuroscience Neural Signaling Reagents & Chemicals Molecules
Type	Molecules
Specific against	other
Smiles	OS(=O)(=O)c1ccccc1.CN(c1ncccc1CNc1nc(Nc2ccc3NC(=O)Cc3c2)ncc1C(F)(F)F)S(C)(=O)=O
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	PF-00562271 Besylate
Shipping Condition	Cool pack
Available
Manufacturer - Targets	FAK\|\|\|PYK2\|\|\|CDK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	665.66
Description	PF-562271 besylate (PF-00562271 Besylate) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.
Pathways	Angiogenesis\|\|\|Tyrosine Kinase/Adaptors\|\|\|Cell Cycle/Checkpoint\|\|\|Cytoskeletal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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