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CHIR-124

CHIR-124

Item no.	TMO-T6350-1mg
Manufacturer	TargetMol
CASRN	405168-58-3
Amount	1 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Oncology Neuroscience Metabolism Diabetes Molecular Targets for Neuroscience Reagents & Chemicals Molecules By Organ Colorectal Cancer
Type	Molecules
Specific against	other
Smiles	Clc1ccc2[nH]c(=O)c(-c3nc4ccccc4[nH]3)c(N[C@@H]3CN4CCC3CC4)c2c1
ECLASS 10.1	32169090
ECLASS 11.0	32169090
UNSPSC	12000000
Alias	CHIR124,CHIR 124
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Chk\|\|\|GSK-3\|\|\|FLT\|\|\|Apoptosis\|\|\|Src\|\|\|PDGFR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	419.91
Description	CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.
Pathways	Angiogenesis\|\|\|PI3K/Akt/mTOR signaling\|\|\|Cell Cycle/Checkpoint\|\|\|Apoptosis\|\|\|Stem Cells\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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