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ER-27319

ER-27319

Item no.	TMO-T78641-25mg
Manufacturer	TargetMol
CASRN	201010-95-9
Amount	25 mg
Quantity options	100 mg 100 mg 25 mg 25 mg 50 mg 50 mg
Category	Oncology Neuroscience Molecular Targets for Neuroscience Peptides & Proteins Cell Biology Cell Status Necrosis Peptides By Organ Thyroid Cancer
Type	Peptides
Specific against	other
Smiles	C(C(O)=O)(O)=O.C(CCN)N1C=2C(C(=O)C=3C1=CC=CC3)=CC=C(C)C2C
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Syk
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	370, 4
Description	ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine phosphorylation and enzymatic activity of SYK. With an inhibitory concentration (IC50) of 10 µM, this compound suppresses the release of allergic mediators from human and rat mast cells triggered by antigens, making it useful for allergy research [1] [2].
Pathways	Angiogenesis\|\|\|Tyrosine Kinase/Adaptors

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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