rTRD01

Item no.	TMO-T81251-50mg
Manufacturer	TargetMol
CASRN	1332175-56-0
Amount	50 mg
Quantity options	50 mg 5 mg
Specific against	other
Smiles	O=C(N)C=1N=C(C=NC1)N2CCCC(CO)(CC3=CC=C(F)C=C3)C2
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	344.38
Description	rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269. The compound can partially disrupt the interaction between TDP-43 and the hexanucleotide RNA repeat associated with the c9orf72 gene, implicated in certain neurodegenerative diseases. rTRD01 holds potential for use in neurodegenerative disease research [1].
Pathways	Others

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