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GLPG3312

GLPG3312

Item no.	TMO-T86509-50mg
Manufacturer	TargetMol
CASRN	2340388-72-7
Amount	50 mg
Quantity options	100 mg 10 mg 10 mg 1 mg 1 mg 200 mg 25 mg 25 mg 50 mg 50 mg 5 mg 5 mg
Category	Oncology By Cell Type Hematology Leukemia Lymphoma Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Smiles	O=C(NC1CC1)C2=C(OC)C=C(C=C2OC(F)F)N3C=NC=4C=C(C=CC43)C=5C=NN(C5)C
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GLPG 3312
Shipping Condition	Cool pack
Available
Manufacturer - Targets	SIK
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	453, 44
Description	GLPG3312 is a selective and potent pan-SIK inhibitor with the advantage of oral activity, with IC50=0.6-2.0 nM for SIK1, SIK2 and SIK3, and exhibits anti-inflammatory and immunomodulatory activity in both human primary myeloid cells and mouse models.
Pathways	PI3K/Akt/mTOR signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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