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AMCase/CHIA Protein, Human, Recombinant (His)

AMCase/CHIA Protein, Human, Recombinant (His)

Item no.	TMO-TMPK-01154-500ug
Manufacturer	TargetMol
Amount	500 ug
Quantity options	100 ug 100 ug 10 ug 1 mg 200 ug 20 ug 500 ug 500 ug 50 ug 5 ug
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	YNL,AMCase,Chia1,CHIA,Acidic mammalian chitinase,EC 3.2.1.14,CHIT2
Shipping Condition	Cool pack
Available
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	51.2 kDa (predicted). Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
Description	Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages' full maturation and polarization.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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