Application Notes |
(3beta, 5alpha, 20R)-Pregnane-3, 20-diol, 20-Sulfate Sodium Salt is sulfate conjugated metabolite of Allopregnandiol (CAS#516-33-0). (3beta, 5alpha, 20R)-Pregnane-3, 20-diol, 20-Sulfate Sodium Salt can be obtained from 5alpha-Pregnan-3beta-ol-20-one 3beta-Acetate (P711315) which is a derivative of Pregnenolone (P712200); a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens. As such it is a prohormone. Pregnenolone is a GABAA antagonist and increases neurogenesis in the hippocampus. It is a modulator of cytochrome P 450-3A. |