RANK, Recombinant, Mouse, Fc (TNFRSF11A, ODFR, Osteoclast Differentiation Factor Receptor, CD265)

Molecular Biology / MB-CD Markers

-20°C

Supplied as a lyophilized powder in PBS. Reconstitute with 50ul sterile ddH2O.

RANK (TRANCE-R; CD265) is the receptor for RANKL/TRANCE/OPGL. It is essential for RANKL-mediated osteoclastogenesis and is involved in the regulation of interactions between T cells and dendritic cells.

Sequence:
Mouse RANK (aa31-214) is fused at the C-terminus to the Fc portion of human IgG1, expressed in HEK 293 cells.

Biological Activity:
Inhibits mouse and human RANKL biological functions.

Specificity:
Binds to mouse and human RANKL.

Storage and Stability:
Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.