Leucine Zipper Tumor Suppressor 1 (LZTS1) Antibody

Leucine Zipper Tumor Suppressor 1 (LZTS1)

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

PBS containing 0.09% sodium azide.

LZTS1

Purified through a protein A column, followed by peptide affinity purification.