Phospho-STING/TMEM173-S366 Rabbit mAb

Phosphorylated Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.09% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

A synthetic phosphorylated peptide around S366 of human STING1 (NP_938023.1).

42kDa

Epigenetics Nuclear Signaling, Cancer, Immunology Inflammation, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway.

340061

STING1