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Anti-CD4 (GK1.5) In Vivo Antibody - Low Endotoxin Europäischer Partner

ArtNr ICH1042-100MG
Hersteller IchorBio
Menge 100 mg
Quantity options 100 mg 1 mg 25 mg 50 mg 5 mg
Kategorie
Typ Antibody
Applikationen WB, FC, IP, IHC, Blocking
Clon GK1.5
Specific against Mouse (Murine, Mus musculus)
Host Rat
Isotype IgG2b Kappa
Purity >95% by SDS-PAGE and HPLC
Citations Cao et al. Injectable hydrogel loaded with lysed OK-432 and doxorubicin for residual liver cancer after incomplete radiofrequency ablation. Journal of Nanobiotechnology
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias T-cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3
Versandbedingung Gekühlt
Lieferbar
Specificity Anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) recognizes an epitope on Mouse CD4
Manufacturer - Applications
Western Blot, Blocking, Flow Cytometry, IHC (Frozen), Immunoprecipitation
Manufacturer - Category
Low Endotoxin, anti-mouse, monoclonal antibody
Manufacturer - Isotype
Rat IgG2b Kappa
Manufacturer - Targets
CD4
Shipping Temperature
Blue ice
Storage Conditions
anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Aggregation
Aggregation level ≤ 5%
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution
The L3T4 antigen is expressed by the helper/inducer subset of mouse T-cells. The antigen is present on approximately 80% of thymocytes, 20% of spleen cells and 60% of lymph node cells. The expression of L3T4 correlates with class II MHC antigen reactivity on cloned T-cell lines.
Application Notes
Blocking: Anti-Mouse CD4 (clone GK1.5) is useful for In vitro and In vivo studies of T-helper cell functions including blocking of ligand binding and T-helper cell activation.
Each investigator should determine their own optimal working dilution for specific applications.
Background
CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.
Concentration
≥ 2.0 mg/ml
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Manufacturer - Specificity
Anti-CD4 In Vivo Antibody - Low Endotoxin (GK1.5) recognizes an epitope on Mouse CD4
Purification method
This monoclonal antibody was purified using Protein G
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Immunogen
Mouse CTL clone V4
Related Antibodies
Isotype Control
Rat IgG2b In Vivo Isotype Control - Low Endotoxin [1-2] (ICH2243)
Buffer
ICH3001-100ml; ICH3002-100ml; ICH3003-100ml

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 mg
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 31.07.2025 

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