Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Menge |
500ug |
Host |
E.coli |
ArtNr |
CSB-EP881354MO-500 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Research Topic |
Cardiovascular |
Uniprot ID |
Q9JM73 |
Gene Names |
Srf |
Organism |
Mus musculus (Mouse) |
AA Sequence |
MLPSQAGAAAALGRGSALGGNLNRTPTGRPGGGGG TRGANGGRVPGNGAGLGQSRLEREAAAAAAPTAGA LYSGSEGDSESGEEEELGAERRGLKRSLSEMELGV VVGGPEAAAAAAGGYGPVSGAVSGAKPGKKTRGRV KIKMEFIDNKLRRYTTFSKRKTGIMKKAYELSTLT GTQVLLLVASETGHVYTFATRKLQPMITSETGKAL IQTCLNSPDSPPRSDPTTDQRMSATGFEEPDLTYQ VSESDSSGETKDTLKPAFTVTNLPGTTSTIQTAPS TSTTMQVSSGPSFPITNYLAPVSASVSPSAVSSAN GTVLKSTGSGPVSSGGLMQLPTSFTLMPGGAVAQQ VPVQAIHVHQAPQQASPSRDSSTDLTQTSSSGTVT LPATIMTSSVPTTVGGHMMYPSPHAVMYAPTSGLA DGSLTVLNAFSQAPSTMQVSHSQVQEPGGVPQVFL TAPSGTVQIPVSAVQLHQMAVIGQQAGSSSNLTEL QVVNLDATHSTKSE |
Expression Region |
1-504aa |
Sequence Info |
Full Length |
Source |
E.coli |
Tag Info |
N-terminal 6xHis-SUMO-tagged |
MW |
67.2 kDa |
Alternative Name(s) |
Short name:SRF |
Relevance |
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) (By similarity). Required for cardiac differentiation and maturation. |
Reference |
"Identification of a novel serum response factor cofactor in cardiac gene regulation."Zhang X., Azhar G., Zhong Y., Wei J.Y.J. Biol. Chem. 279:55626-55632(2004) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS) (By similarity). Required for cardiac differentiation and maturation. |
Subcellular Location |
Nucleus |
Tag Information |
N-terminal 6xHis-SUMO-tagged |
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