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Recombinant Human Hyaluronidase-1(HYAL1)

ArtNr CSB-YP623651HU-10
Hersteller Cusabio
Menge 10 ug
Quantity options 1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host Yeast
Konjugat/Tag HIS
Purity Greater than 90% as determined by SDS-PAGE.
Sequence FRGPLLPNRPFTTVWNANTQWCLERHGVDVDVSVF DVVANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEP VFGGLPQNASLIAHLARTFQDILAAIPAPDFSGLA VIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQHPD WPAPQVEAVAQDQFQGAARAWMAGTLQLGRALRPR GLWGFYGFPDCYNYDFLSPNYTGQCPSGIRAQNDQ LGWLWGQSRALYPSIYMPAVLEGTGKSQMYVQHRV AEA
Protein Familie Glycosyl hydrolase 56 family
Citations Structure of human hyaluronidase-1, a hyaluronan hydrolyzing enzyme involved in tumor growth and angiogenesis.Chao K.L., Muthukumar L., Herzberg O.Biochemistry 46:6911-6920(2007)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Hyaluronoglucosaminidase-1Lung carcinoma protein 1 ;LuCa-1
Lieferbar
Manufacturer - Conjugate / Tag
N-terminal 6xHis-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
48.1 kDa
General Research Areas
Cancer
Relevance
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
Expression Region
22-435aa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
Subcellular Location
Secreted, Lysosome
Tissue Specificity
Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues.
Involvement in disease
Mucopolysaccharidosis 9 (MPS9)
Gene Names
HYAL1
Sequence Info
Full Length of Mature Protein
Organism
Homo sapiens (Human)
Storage Buffer
Tris-based buffer, 50% glycerol

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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