PE/Cyanine5.5 Anti-Human CD11a Antibody[TS1/22.1.1.13]

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1alpha chain and integrin alphaL subunit. CD11a non-covalently associates with integrin beta2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).