Sonic Hedgehog (Shh), Mouse

Hersteller GenScript
Typ Proteins
Specific against Mouse
Menge 1.0mg 
ArtNr Z02990-1
Eclass 6.1 34160400
Eclass 9.0 42020190
Product Line
Cytokines, Chemokines & Growth Factors
Sonic Hedgehog (Shh), is a member of the Hedgehog (Hh) family of highly conserved proteins which are widely represented throughout the animal kingdom. In mammal, there are threerelatedHh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh). They share a high degree of amino-acid sequence identity (e.g. Shh and Ihh are 93% identical). Sonic Hedgehog plays a role in cell growth, cell specialization, and the normal shaping (patterning) of the body. Shh is also important for development of the brain and spinal cord (central nervous system), eyes, limbs, and many other parts of the body. Recombinant, mouseSonic Hedgehog(rmShh), produced in, E.coli, is a single non-glycosylated polypeptide chain containing 176 amino acids. A fully biologically active molecule, rmShh, is obtained by proprietary chromatographic techniques at GenScript with a molecular mass of 19.8kDa analyzed by reducing SDS-PAGE.
19.8kDa, observed by reducing SDS-PAGE.
> 95% by SDS-PAGE and HPLC analyses.
Endotoxin Level
<0.2 EU/ug, determined by LAL method.
Specific Activity
ED50 1.0x 103units/mg.
Lyophilized recombinant, mouseSonic Hedgehog(rmShh) remains stable up to 6 months at -80C from date of receipt. Upon reconstitution, rmShhshould be stable up to 2 weeks at 4C or up to 3 months at -20C.
Lyophilized after extensive dialysis against PBS.
Reconstituted in ddH2O at 100 ug/ml.
Cys25-Gly198 (Cys25Ile-Val-Ile)(accession number:Q62226).
For research use only
Menge: 1.0mg 
Lieferbar: In stock
Listenpreis: 1.290,30 €
Preis: 1.290,30 €

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