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LY75 Antibody (Center)

LY75 Antibody (Center)

ArtNr	ABC-AP8994c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	LY75, CD205, CLEC13B, DEC-205, C-type lectin domain family 13 member B, gp200-MR6, Ly-75, Lymphocyte antigen 75
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Primary Accession	O60449
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	LY75 acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. It causes reduced proliferation of B-lymphocytes.
Bio References	Kato, M., et.al., Immunogenetics 47 (6), 442-450 (1998) McKay, P.F., et.al., Eur. J. Immunol. 28 (12), 4071-4083 (1998)
Clonality	Polyclonal
Clone/Animal Names	RB23558
Gene ID	100526664; 4065
Gene Name	LY75
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of LY75 Antibody (Center) (Cat. #AP8994c) in HL-60 cell line lysates (35ug/lane). LY75 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	Formalin-fixed and paraffin-embedded human spleen tissue reacted with LY75 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Legend image 3	LY75 Antibody (Center) (Cat. #AP8994c) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Isotype	Rabbit Ig
Calculated MW	198311
Antigen Region	646-675
Antigen Source	HUMAN
Target/Specificity	This LY75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-675 amino acids from the Central region of human LY75.
NCBI Accession	NP_001185688.1; NP_001185689.1; NP_002340.2

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Menge: 400 ul

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