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SARS-COV-2 PLpro/papain-like protease Protein (COV-VE1PL)

SARS-COV-2 PLpro/papain-like protease Protein (COV-VE1PL)

ArtNr	COV-VE1PL-100UG
Hersteller	KactusBio
Menge	100 ug
Quantity options	100 ug 500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Specific against	SARS-CoV-2
Host	E.coli
Konjugat/Tag	HIS
Purity	> 95% as determined by Bis-Tris PAGE
Formula	Supplied as 0.22μm filtered solution in 20mM Tris, 100mM NaCl, 10% Glycerol (pH 8.5).
Dry ice	Yes
Sequence	Glu1564-Val1880
NCBI	YP_009725299.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Replicase polyprotein 1a,pp1a,nsp1,PL2-PRO,PL-PRO,Papain-like Protease,Plpro
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	PLpro/papain-like protease
Manufacturer - Conjugate / Tag	N-His
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 39.2 kDa same as Bis-Tris PAGE result.
Description	Recombinant SARS-COV-2 PLpro/papain-like protease Protein is expressed from E.coli with His tag at the N-Terminus.It contains Glu1564-Val1880.
Background	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in 20mM Tris, 100mM NaCl, 10% Glycerol (pH 8.5).
Biotinylated	no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

COV-VE1PL-100UG-datasheet.pdf

COV-VE1PL-100UG-safety-datasheet.pdf