Sodium Starch Glycolate

Biochemicals / Biochem-Fine Chemicals

4°C

White to off-white powder

Sodium carboxyl methyl starch is a modified starch that is used as an excipient in many pharmaceutical products. It has been shown to reduce the rate of drug absorption by slowing down gastric emptying and increasing the viscosity of the gastrointestinal tract. Sodium carboxyl methyl starch has been used to control the release of paliperidone, a drug used for the treatment of schizophrenia and bipolar disorder. This agent is not known to be toxic to humans or animals, with no adverse effects observed following oral administration. The use of sodium carboxyl methyl starch in wastewater treatment has been investigated as a way to remove anions such as phosphate and nitrate from water.

Synonyms:
Carboxymethyl Starch Sodium Salt; Covagel; Crayon B 300P; Deprogel; Emsize CMS 100; Emsize CMS 60; Estarl A 100; Explosol; Explotab; Explotab CL-V; Expotab PCF; F 500 Papeal No. 50; Glycol YS; Glycolys LV; Glycolys Std; KMK-BUR 1; KMK-OK; Kiprogum F 500; LCW Covagel; Libeng; P 5000; Papeal F 500 No. 50; Polvitex Z; Polytex 60; Primojel; Sodium CM-starch; Sodium Carboxymethyl Starch; Solvitose CL; Vivastar P; Vivastar P 3500; Vivastar P 5000; WS 1R; Walocel CRT 100GA; USP Sodium Starch Glycolate Type A

CAS No:
9063-38-1

Molecular Formula:
(C2H4O3)x•(Na)x

Molecular Weight:
NA

Appearance:
White to off-white powder

Purity:
≥95%

1H-NMR:
Conforms to reference

Melting Point:
>210°C (dec.)

Solubility:
Practically insoluble in methylene chloride. It gives a translucent suspension in water.

Storage and Stability:
May be stored at RT for short-term only. Long-term storage is recommended at 4°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.