Diuron-d6

ArtNr	HY-B0860S-100mg
Hersteller	MedChem Express
CAS-Nr.	1007536-67-5
Menge	100 mg
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Kategorie	Reagents & Chemicals Biochemicals
Typ	Chemicals
Specific against	other
Purity	99.00
Citations	[1]Huovinen M, et al. Toxicity of diuron in human cancer cells. Toxicol In Vitro. 2015 Oct;29(7):1577-86.\|[2]Lundegårdh H. THE INFLUENCE OF DIURON (3-(3,4-DICHLOROPHENYL)-1,1-DIMETHYLUREA) ON THE RESPIRATORY AND PHOTOSYNTHETIC SYSTEMS OF PLANTS. Proc Natl Acad Sci U S A. 1965 Apr;53(4):703-10.\|[3]Da Rocha MS, et al. Diuron-induced rat urinary bladder carcinogenesis: mode of action and human relevance evaluations using the International Programme on Chemical Safety framework. Crit Rev Toxicol. 2014 May;44(5):393-406. \|[4]Chauhan L K S, et al. Diuron-induced cytological and ultrastructural alterations in the root meristem cells ofAllium cepa. Pesticide Biochemistry and Physiology, 1998, 62(3): 152-163. \|[5]Da Rocha MS, et al. Diuron-induced rat bladder epithelial cytotoxicity. Toxicol Sci. 2012 Dec;130(2):281-8.\|[6]de Moura NA, et al. Potential effects of the herbicide Diuron on mammary and urinary bladder two-stage carcinogenesis in a female Swiss mouse model. Arch Toxicol. 2010 Feb;84(2):165-73.
Smiles	[2H]C([2H])([2H])N(C([2H])([2H])[2H])C(NC1=CC(Cl)=C(C=C1)Cl)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Targets	Herbicide; Isotope-Labeled Compounds; MDM-2/p53; Reactive Oxygen Species (ROS)
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	239.13
Product Description	Diuron-d6 is the deuterium labeled Diuron (HY-B0860). Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research[1][2][3][4][5][6].
Manufacturer - Research Area	Cancer
Solubility	DMSO: ≥ 100 mg/mL
Manufacturer - Pathway	Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Clinical information	No Development Reported

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Menge: 100 mg

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