Comparison

Diuron-d6 European Partner

Item no. HY-B0860S-100mg
Manufacturer MedChem Express
CASRN 1007536-67-5
Amount 100 mg
Quantity options 100 mg 10 mg 1 ea 1 mg 5 mg
Category
Type Chemicals
Specific against other
Purity 99.00
Citations [1]Huovinen M, et al. Toxicity of diuron in human cancer cells. Toxicol In Vitro. 2015 Oct;29(7):1577-86.|[2]Lundegårdh H. THE INFLUENCE OF DIURON (3-(3,4-DICHLOROPHENYL)-1,1-DIMETHYLUREA) ON THE RESPIRATORY AND PHOTOSYNTHETIC SYSTEMS OF PLANTS. Proc Natl Acad Sci U S A. 1965 Apr;53(4):703-10.|[3]Da Rocha MS, et al. Diuron-induced rat urinary bladder carcinogenesis: mode of action and human relevance evaluations using the International Programme on Chemical Safety framework. Crit Rev Toxicol. 2014 May;44(5):393-406. |[4]Chauhan L K S, et al. Diuron-induced cytological and ultrastructural alterations in the root meristem cells ofAllium cepa. Pesticide Biochemistry and Physiology, 1998, 62(3): 152-163. |[5]Da Rocha MS, et al. Diuron-induced rat bladder epithelial cytotoxicity. Toxicol Sci. 2012 Dec;130(2):281-8.|[6]de Moura NA, et al. Potential effects of the herbicide Diuron on mammary and urinary bladder two-stage carcinogenesis in a female Swiss mouse model. Arch Toxicol. 2010 Feb;84(2):165-73.
Smiles [2H]C([2H])([2H])N(C([2H])([2H])[2H])C(NC1=CC(Cl)=C(C=C1)Cl)=O
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Shipping Condition Room temperature
Available
Manufacturer - Type
Isotope-Labeled Compounds
Manufacturer - Targets
Herbicide; Isotope-Labeled Compounds; MDM-2/p53; Reactive Oxygen Species (ROS)
Shipping Temperature
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight
239.13
Product Description
Diuron-d6 is the deuterium labeled Diuron (HY-B0860). Diuron is an orally active phenylurea herbicide. Diuron inhibits photosynthesis in plants by blocking the formation of ATP and NADH. Diuron increases the production of ROS. Diuron increases expression of p53 in certain cell lines. Diuron has herbicidal activity against annual and perennial broadleaf weeds and grass weeds. Diuron promotes DMBA/BBN-induced bladder cancer. Diuron can be used in breast cancer research[1][2][3][4][5][6].
Manufacturer - Research Area
Cancer
Solubility
DMSO: ≥ 100 mg/mL
Manufacturer - Pathway
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Clinical information
No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 mg
Available: In stock
available

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