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Asialoglycoprotein Receptor 1 (ASGR1) Antibody

Asialoglycoprotein Receptor 1 (ASGR1) Antibody

Manufacturer	Abbexa
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Primary
Specific against	Human
Isotype	IgG
Applications	WB
Amount	400 ul
Host	Rabbit
Item no.	abx028618-400
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Antigen	Asialoglycoprotein Receptor 1 (ASGR1)
Description	Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Conjugation	Unconjugated
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P07306
UniProt Entry Name	ASGR1_HUMAN
Gene Symbol	ASGR1
Gene ID	432
OMIM	108360
Buffer	PBS containing 0.09% sodium azide.
Dry Ice	No
Note	This product is for research use only.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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