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DR5/TRAILR2/TNFRSF10B Rabbit pAb

DR5/TRAILR2/TNFRSF10B Rabbit pAb

Manufacturer	Abclonal
Category	Oncology Antibodies By Cell Type Carcinoma Hematology Myeloma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Primary Antibodies By Organ Lung Cancer Bladder Cancer Colorectal Cancer Breast Cancer Testicular & Prostate Cancer
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	WB, ELISA
Amount	200ul
Host	Rabbit
Item no.	A1236-200ul
Targets	CD262
Conjugate/Tag	Unconjugated
eClass 6.1	32160702
eClass 9.0	32160702
Available
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
Route	Recombinant protein
Manufacturers Category	Polyclonal Antibodies
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 260-440 of human DR5/TRAILR2/TNFRSF10B (NP_003833.4).
Storage	Store at -20℃. Avoid freeze / thaw cycles.\|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilution	WB, 1:500 - 1:2000
Protein Size	48kDa
Manufacturers Research Area	Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Growth factors, Death Receptor Signaling Pathway, Immunology Inflammation, CDs, NF-kB Signaling Pathway
Gene Symbol	TNFRSF10B

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 200ul

available

Delivery expected until 7/2/2024