Phospho-GSK3β-Y216 + GSK3α-Y279 Rabbit pAb

Phosphorylated Antibodies

Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

A synthetic phosphorylated peptide around Y216 of human GSK3β (NP_001139628).

47kDa

Epigenetics & Nuclear Signaling, Translation Control, Regulation of eIF4 and p70 S6 Kinase, Regulation of eIF2, Cancer, Signal Transduction, Kinase, Serine/threonine kinases, PI3K-Akt Signaling Pathway, mTOR Signaling Pathway, ErbB-HER Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology & Developmental Biology, Apoptosis, Inhibition of Apoptosis, Cell Cycle, Centrosome, G1/S Checkpoint, Cell Adhesion, Microtubules, Hedgehog Signaling Pathway, Wnt/β-Catenin Signaling Pathway, ESC Pluripotency and Differentiation, Endocrine & Metabolism, Carbohydrate metabolism, Insulin Receptor Signaling Pathway, Endocrine and metabolic diseases, Diabetes, Immunology & Inflammation, B Cell Receptor Signaling Pathway, NF-kB Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Neurodegenerative Diseases Markers, Other Neurological disorders, Stem Cells, Cardiovascular, Heart, Hypertrophy, Akt downstream targets, Protein phosphorylation.

2931/2932

GSK3B