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Granzyme B

Granzyme B

Manufacturer	Abclonal
Type	Antibody Polyclonal
Specific against	Human, Mouse
Applications	WB, FC, IHC
Protein Family	Lymphocyte Signaling
Amount	100ug
Host	Rabbit
Item no.	A0376
eClass 6.1	32160702
eClass 9.0	32160702
Available
*	DESCRIPTION
Calculated MW	28kDa
Immunogen	A synthetic peptide of human GZMB
Gene ID	3002
Swiss Prot	P10144
Synonyms	HLP; CCPI; CGL1; CSPB; SECT; CGL-1; CSP-B; CTLA1; CTSGL1;
Isotype	IgG
Purity	Affinity purification
Storage Buffer	Store at 4? or -20?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Recommended Dilutions	WB 1:500-1:1000 IHC 1:50-1:100 FC 1:20-1:50
illustration	Western blot analysis of extracts of mouse stomach celllines, using GZMB antibody.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.